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  Name:  Isaac J Powell, MD  
  Gender:  Male  
  Degree(s):  MD  
  Group Name:  University Physician Group Urology  
  Department Name:  Urology  
  Specialties:  Urology  
  Areas of Interest:  Prostate Cancer, Urologic Oncology  
  Board Certifications:  Am Bd Urology - Board Certified  
Hospital Affiliations are listed in alphabetical order
Detroit Receiving Hospital, Harper University Hospital, Hutzel Women's Hospital, Karmanos Cancer Center, Rehabilitation Institute of Michigan  
  Featured Message:  Dr. Isaac Powell practices urologic oncology with an interest in prostate cancer.  
Karmanos Cancer Center
4100 John R
Detroit, MI 48201-2013
Telephone: 800-527-6266

Primary Office Location

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Rehabilitation Institute of MI
261 Mack Ave
Detroit, MI 48201-2417
Telephone: 313-745-4600

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Dr. Isaac Powell practices urologic oncology with an interest in prostate cancer. His grant funded research interests are in the genetics of prostate cancer development and the influence of race on cancer behavior, particularly in African American men. Dr. Powell is a thought leader in prostate cancer and has published extensively on this disease process.

The focus of my research is on the many ways prostate cancer impacts African Americans in comparison to other ethnic groups. Currently my research is directed toward ethnic differences in the biology/genetics of prostate cancer. I was principle investigator of a nation-wide consortium of recruitment centers (medical centers) to recruit families to examine hereditary prostate cancer among African Americans. We recently reported our initial results of 4 or 5 regions in the genome where genes responsible for hereditary prostate cancer may be found. As a part of an International consortium genetics group, we are comparing our results with other centers around the world. In collaboration with others at our institutions and other institutions across the United States, we are examining the androgen gene variation. We are also studying environmental factors that impact on genes such as diet and inflammation in correlation to clinical outcome. I was recently funded to examine Metabolic Syndrome and Prostate Cancer. We recently completed a study using the DASL technique and found that 60% of the prostate cancer genes that are differentially expressed and associated with advanced disease are different among African American compared to European American men.

Medical Training:

  • Internship, Henry Ford Hospital, Detroit, Michigan, 1969-1970
  • General Surgery Residency, Henry Ford Hospital, Detroit, Michigan, 1970-1971
  • Urology Residency, Henry Ford Hospital, Detroit, Michigan, 1971-1974


  • University of Michigan, Ann Arbor, Michigan: B.S. in Zoology, 1962
  • Howard University Graduate School, Washington, DC: M.S. in Embryology, 1965
  • Indiana University Medical School, Indianapolis, Indiana: M.D., 1969

Awards and Other Professional Activities:

  • Professional Appointments/Societies
  • Past Board of Directors of Physicians Insurance Company of Michigan (PICOM)
  • Past Vice Chairman of the Board and past Chairman of the Underwriting Committee and Risk Management Committee
  • Past President of Michigan Urological Society (1988-1989)
  • Wayne County Medical Society
  • Michigan State Medical Society
  • Detroit Medical Society
  • American Urological Association
  • Society of Basic Urologic Research
  • Society of Urologic Oncology
  • Southwest Oncology Group (SWOG)
  • American Cancer Society, National Advisory Group on Prostate Cancer
  • Prostate Cancer Education Council
  • International Consortium for Prostate Cancer Genetics (I.C.P.C.G.)
  • American Association Cancer Research #20510


  • 1998 President’s Achievement Award for Community Research
  • 1st International Prostate Cancer symposium for the patient 1998 Medical Professional Advocate Award
  • Howard University Cancer Center Award
  • Michiganian of the Year Award, 1995
  • Michigan Cancer Foundation Distinguished Service Award
  • The MDPH Distinguished Dr. Martin Luther King Award
  • Centers for Disease Control and Prevention the Department of Health & Human Service: Outstanding Community Health Promotion Program
  • 2001 American Cancer Society Award In Appreciation for the Commitment to Help Find a Cure
    Karmanos Partners Award for Prostate Cancer Research
  • 2003 Crain’s Detroit Business Magazine, “Healthcare Hero’s”: Outstanding Physician Achievement Award
  • 2003 America’s Top Physicians
  • 2007 Best Doctors - 2002, 2003 and 2007